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Issue 12, 2014
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Wide-field Raman imaging of dental lesions

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Detection of dental caries at the onset remains as a great challenge in dentistry. Raman spectroscopy could be successfully applied towards detecting caries since it is sensitive to the amount of Raman active mineral crystals, the most abundant component of enamel. Effective diagnosis requires full examination of a tooth surface via Raman mapping. Point-scan Raman mapping is not clinically relevant (feasible) due to lengthy data acquisition time. In this work, a wide-field Raman imaging system was assembled based on a high-sensitivity 2D CCD camera for imaging the mineralization status of teeth with lesions. Wide-field images indicated some lesions to be hypomineralized and others to be hypermineralized. The observations of wide-field Raman imaging were in agreement with point-scan Raman mapping. Therefore, sound enamel and lesions can be discriminated by Raman imaging of the mineral content. In conclusion, wide-field Raman imaging is a potentially useful tool for visualization of dental lesions in the clinic.

Graphical abstract: Wide-field Raman imaging of dental lesions

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The article was received on 22 Jan 2014, accepted on 26 Mar 2014 and first published on 26 Mar 2014

Article type: Paper
DOI: 10.1039/C4AN00164H
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Analyst, 2014,139, 3107-3114

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    Wide-field Raman imaging of dental lesions

    S. Yang, B. Li, A. Akkus, O. Akkus and L. Lang, Analyst, 2014, 139, 3107
    DOI: 10.1039/C4AN00164H

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