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Issue 22, 2014
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DNA bioassay-on-chip using SERS detection for dengue diagnosis

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Abstract

A novel DNA bioassay-on-chip using surface-enhanced Raman scattering (SERS) on a bimetallic nanowave chip is presented. In this bioassay, SERS signals were measured after a single reaction on the chip's surface without any washing step, making it simple-to-use and reducing the reagent cost. Using the technique, specific oligonucleotide sequences of the dengue virus 4 were detected.

Graphical abstract: DNA bioassay-on-chip using SERS detection for dengue diagnosis

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Article information


Submitted
15 Jun 2014
Accepted
01 Sep 2014
First published
02 Sep 2014

Analyst, 2014,139, 5655-5659
Article type
Communication

DNA bioassay-on-chip using SERS detection for dengue diagnosis

H. T. Ngo, H. Wang, A. M. Fales, B. P. Nicholson, C. W. Woods and T. Vo-Dinh, Analyst, 2014, 139, 5655
DOI: 10.1039/C4AN01077A

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