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Issue 11, 2014
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Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region

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Abstract

Fibrillar distribution in the rat tail tendon and mice liver can be measured using optical methods. Two-photon excitation provides easy assessment of fibrotic collagen types I and II. Single photon deep ultraviolet (DUV) excitation imaging highlights all collagen types without discrimination. Their combination on the same tissue area provides a better overview of collagens in fibrillar diseases.

Graphical abstract: Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region

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Article information


Submitted
27 Jan 2014
Accepted
20 Mar 2014
First published
21 Mar 2014

Analyst, 2014,139, 2663-2667
Article type
Communication
Author version available

Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region

V. Zubkovs, F. Jamme, S. Kascakova, F. Chiappini, F. Le Naour and M. Réfrégiers, Analyst, 2014, 139, 2663
DOI: 10.1039/C4AN00203B

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