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Issue 48, 2013
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Liposome-like nanostructures for drug delivery

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Liposomes are a class of well-established drug carriers that have found numerous therapeutic applications. The success of liposomes, together with recent advancements in nanotechnology, has motivated the development of various novel liposome-like nanostructures with improved drug delivery performance. These nanostructures can be categorized into five major varieties, namely: (1) polymer-stabilized liposomes, (2) nanoparticle-stabilized liposomes, (3) core–shell lipid–polymer hybrid nanoparticles, (4) natural membrane-derived vesicles, and (5) natural membrane coated nanoparticles. They have received significant attention and have become popular drug delivery platforms. Herein, we discuss the unique strengths of these liposome-like platforms in drug delivery, with a particular emphasis on how liposome-inspired novel designs have led to improved therapeutic efficacy, and review recent progress made by each platform in advancing healthcare.

Graphical abstract: Liposome-like nanostructures for drug delivery

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Publication details

The article was received on 06 Sep 2013, accepted on 09 Oct 2013 and first published on 09 Oct 2013

Article type: Feature Article
DOI: 10.1039/C3TB21238F
J. Mater. Chem. B, 2013,1, 6569-6585

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    Liposome-like nanostructures for drug delivery

    W. Gao, C. J. Hu, R. H. Fang and L. Zhang, J. Mater. Chem. B, 2013, 1, 6569
    DOI: 10.1039/C3TB21238F

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