Graphene oxide-based homogenous biosensing platform for ultrasensitive DNA detection based on chemiluminescence resonance energy transfer and exonuclease III-assisted target recycling amplification†
Abstract
We report an amplified chemiluminescence (CL) biosensing platform for ultrasensitive DNA detection. It is based on exonuclease III-assisted target recycling amplification and the super quenching efficiency of graphene oxide (GO). In the presence of target DNA, the target–probe hybrid forms a double-stranded structure, and exonuclease III catalyzes the stepwise removal of