Jump to main content
Jump to site search

Issue 22, 2013
Previous Article Next Article

Mapping the mechanical properties of biomaterials on different length scales: depth-sensing indentation and AFM based nanoindentation

Author affiliations

Abstract

The micro- and nanomechanical properties of biomaterials are of central importance as surface elasticity, surface elastic response and adhesion play a central role in a large number of biological processes. They influence, e.g. morphogenesis, self-healing abilities and restoration processes, focal adhesion, motility, mechano-transduction, metastasis and are important for drug delivery applications, and others. These processes address fundamental questions in biology, medicine and diagnostics, pharmaceutical research, archaeology, dental as well as cosmetic applications. With nanoindentation as well as AFM force spectroscopic techniques suitable investigation tools are at hand, which can provide mechanical information on different length scales. The development of both techniques resulted in a broad applicability and the number of examples where both techniques have been used to study (soft) biomaterials rapidly increased during the last years.

Graphical abstract: Mapping the mechanical properties of biomaterials on different length scales: depth-sensing indentation and AFM based nanoindentation

Back to tab navigation

Publication details

The article was received on 25 Jan 2013, accepted on 19 Mar 2013 and first published on 19 Mar 2013


Article type: Feature Article
DOI: 10.1039/C3TB20120A
J. Mater. Chem. B, 2013,1, 2789-2806

  •   Request permissions

    Mapping the mechanical properties of biomaterials on different length scales: depth-sensing indentation and AFM based nanoindentation

    E. Rettler, S. Hoeppener, B. W. Sigusch and U. S. Schubert, J. Mater. Chem. B, 2013, 1, 2789
    DOI: 10.1039/C3TB20120A

Search articles by author

Spotlight

Advertisements