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Issue 36, 2013
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Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

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Abstract

We review some of the recent progresses made by the application of polymer physics to the understanding of the spatial organization of chromosomes in the cell nucleus. In particular, we focus on some scaling properties of the contact probability of pairs of sites, discovered by recent genome-wide experiments exploiting new technologies such as Hi-C methods.

Graphical abstract: Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

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Article information


Submitted
22 May 2013
Accepted
10 Jul 2013
First published
11 Jul 2013

Soft Matter, 2013,9, 8631-8635
Article type
Review Article

Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

M. Barbieri, A. Scialdone, A. Gamba, A. Pombo and M. Nicodemi, Soft Matter, 2013, 9, 8631
DOI: 10.1039/C3SM51436F

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