Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 6, 2013
Previous Article Next Article

Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP

Author affiliations

Abstract

A metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP is established for the synthesis of 3-(2-oxoethyl)indolin-2-ones. This method allows 1,2-difunctionalization of the C–C double bond in N-arylacrylamides by simultaneous formation of two C(sp2)–C(sp3) bonds.

Graphical abstract: Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Mar 2013, accepted on 17 Apr 2013 and first published on 17 Apr 2013


Article type: Edge Article
DOI: 10.1039/C3SC50810B
Chem. Sci., 2013,4, 2690-2694

  •   Request permissions

    Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP

    M. Zhou, R. Song, X. Ouyang, Y. Liu, W. Wei, G. Deng and J. Li, Chem. Sci., 2013, 4, 2690
    DOI: 10.1039/C3SC50810B

Search articles by author

Spotlight

Advertisements