Jump to main content
Jump to site search

Issue 1, 2013
Previous Article Next Article

Compact tridentate ligands for enhanced aqueous stability of quantum dots and in vivo imaging

Author affiliations

Abstract

We describe here a simple and versatile route for the preparation of a tridentate ligand that not only provides stable interactions with colloidal semiconductor nanocrystals (quantum dots, QDs) but also makes them water soluble. The designed ligand incorporates a biocompatible solubilizing polyethylene glycol (PEG) chain connected to a tridentate thiol motif with improved affinity towards the QDs surface. Stability experiments revealed better resistance to various drastic conditions compared to classical dihydrolipoic-based ligands. The enhanced stability of the assembly also enabled in vivo imaging experiments using near infrared-emitting QDs.

Graphical abstract: Compact tridentate ligands for enhanced aqueous stability of quantum dots and in vivo imaging

Back to tab navigation

Supplementary files

Article information


Submitted
30 Jul 2012
Accepted
10 Oct 2012
First published
11 Oct 2012

Chem. Sci., 2013,4, 411-417
Article type
Edge Article

Compact tridentate ligands for enhanced aqueous stability of quantum dots and in vivo imaging

E. Gravel, C. Tanguy, E. Cassette, T. Pons, F. Knittel, N. Bernards, A. Garofalakis, F. Ducongé, B. Dubertret and E. Doris, Chem. Sci., 2013, 4, 411
DOI: 10.1039/C2SC21113K

Social activity

Search articles by author

Spotlight

Advertisements