Nanocrystalline zinc peroxide mediated unprecedented nitrene transfer: an expeditious access to N-tosylaziridines

Abstract

An unprecedented zinc peroxide (ZnO₂) assisted synthetic strategy is reported for the synthesis of N-tosylaziridines from alkenes by using N-tosyliminotriphenylphosphorane (Ph₃PNTs) as a nitrene transfer reagent under mild reaction conditions. The reaction of zinc peroxide with Ph₃PNTs yielded a zinc oxaziridine intermediate which subsequently reacts with alkenes to give corresponding N-tosylaziridines in high to excellent yields.