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Issue 41, 2013
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Copper-catalysed amidation of 2-chloro-pyridines

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Abstract

The simple and inexpensive N,N-dimethylcyclohexane-1,2-diamine/CuI catalytic system provides a versatile, easy and efficient access to an array of N-(2-pyridin-2-yl)-amides from 2-chloro-pyridine derivatives.

Graphical abstract: Copper-catalysed amidation of 2-chloro-pyridines

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Publication details

The article was received on 12 Jun 2013, accepted on 17 Jul 2013 and first published on 19 Jul 2013


Article type: Communication
DOI: 10.1039/C3RA43368D
RSC Adv., 2013,3, 18787-18790

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    Copper-catalysed amidation of 2-chloro-pyridines

    L. Nicolas, P. Angibaud, I. Stansfield, L. Meerpoel, S. Reymond and J. Cossy, RSC Adv., 2013, 3, 18787
    DOI: 10.1039/C3RA43368D

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