Synthesis of novel spiro[indoline-3,7′-pyrrolo[1,2-c]imidazole]-6′-carbonitrile derivatives in water using a regioselective sequential three component reaction†
Abstract
A novel and straightforward method for the synthesis of pharmacologically promising spiro[indoline-3,7′-pyrrolo[1,2-c]imidazole]-6′-carbonitrile derivatives has been developed by a sequential three component one-pot reaction of