Issue 44, 2013
From the journal:

RSC Advances

Bio-based green solvent mediated disulfide synthesis via thiol couplings free of catalyst and additive†

Yunyun Liu,ab   Hang Wang,b   Chunping Wang,b   Jie-Ping Wan*ab  and  Chengping Wen*c  

* Corresponding authors

a Key Laboratory of Functional Small Organic Molecules, Ministry of Education, Jiangxi Normal University, Nanchang 330022, P R China

b College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P R China
E-mail: wanjieping@gmail.com
Fax: +86 791 88120380
Tel: +86 791 88120380

c College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, P R China
E-mail: cpwen.zcmu@yahoo.com
Fax: +86 571 86633131
Tel: +86 571 86633131

Abstract

The bio-based green solvent ethyl lactate has been found to be a particularly efficient medium for oxidative coupling reactions of thiols yielding a broad array of disulfides. As a green solvent, ethyl lactate has shown an interesting promotion effect on the transformation by mediating corresponding reactions with high efficiency without using any catalyst or additive.

Graphical abstract: Bio-based green solvent mediated disulfide synthesis via thiol couplings free of catalyst and additive

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Article information

DOI
https://doi.org/10.1039/C3RA42915F
Article type
Communication
Submitted
12 Jun 2013
Accepted
17 Sep 2013
First published
18 Sep 2013

RSC Adv., 2013,3, 21369-21372

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Bio-based green solvent mediated disulfide synthesis via thiol couplings free of catalyst and additive

Y. Liu, H. Wang, C. Wang, J. Wan and C. Wen, RSC Adv., 2013, 3, 21369 DOI: 10.1039/C3RA42915F

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