Issue 40, 2013

Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS

Abstract

This review discusses the biosynthesis of natural products generated by iterative hybrid polyketide synthases–non ribosomal peptide synthetases (PKS–NRPS) from fungi and bacteria, the programming of the enzymes and bioengineering approaches.

Graphical abstract: Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS

Article information

Article type
Review Article
Submitted
30 May 2013
Accepted
16 Jul 2013
First published
16 Aug 2013
This article is Open Access
Creative Commons BY license

RSC Adv., 2013,3, 18228-18247

Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS

K. M. Fisch, RSC Adv., 2013, 3, 18228 DOI: 10.1039/C3RA42661K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements