Issue 34, 2013
From the journal:

RSC Advances

A FRET operated sensor for intracellular pH mapping: strategically improved efficiency on moving from an anthracene to a naphthalene derivative†

Arnab Banerjee,a   Animesh Sahana,a   Sisir Lohar,a   Bidisha Sarkar,b   Subhra Kanti Mukhopadhyayb  and  Debasis Das*a  

* Corresponding authors

a Department of Chemistry, The University of Burdwan, Burdwan-713104, West Bengal, India

b Department of Microbiology, The University of Burdwan, Burdwan-713104, West Bengal, India
E-mail: ddas100in@yahoo.com
Fax: +91-342-2530452
Tel: +91-342-2533913

Abstract

Two novel fluorescent probes based on anthracene (AAC) and naphthalene (ANC) have been synthesised and characterised. Both the AAC and ANC derivative show green fluorescence at basic pH, but at acidic pH AAC is non-fluorescent, while ANC emits red light. This is attributed primarily to the FRET on–off processes. ANC has better pH discrimination abilities than AAC and can be used to distinguish between different pH environments inside a living cell for the first time.

Graphical abstract: A FRET operated sensor for intracellular pH mapping: strategically improved efficiency on moving from an anthracene to a naphthalene derivative

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Article information

DOI
https://doi.org/10.1039/C3RA41591K
Article type
Paper
Submitted
03 Apr 2013
Accepted
31 May 2013
First published
03 Jun 2013

RSC Adv., 2013,3, 14397-14405

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A FRET operated sensor for intracellular pH mapping: strategically improved efficiency on moving from an anthracene to a naphthalene derivative

A. Banerjee, A. Sahana, S. Lohar, B. Sarkar, S. K. Mukhopadhyay and D. Das, RSC Adv., 2013, 3, 14397 DOI: 10.1039/C3RA41591K

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