Issue 17, 2013

Peptide nucleic acids are an additional class of aptamers

Abstract

Peptide nucleic acids (PNAs) have been known for their similar or superior properties to DNA or RNA since 1991, but not regarded as a separate class of aptamers. We report here an interesting additional property of PNAs revealed by graphene oxide (GO)-based assays, suggesting that nucleobases in certain aptamers play more important roles in strong and selective binding to the target molecules.

Graphical abstract: Peptide nucleic acids are an additional class of aptamers

Supplementary files

Article information

Article type
Communication
Submitted
31 Jan 2013
Accepted
06 Mar 2013
First published
06 Mar 2013

RSC Adv., 2013,3, 5828-5831

Peptide nucleic acids are an additional class of aptamers

E. J. Lee, H. K. Lim, Y. S. Cho and S. S. Hah, RSC Adv., 2013, 3, 5828 DOI: 10.1039/C3RA40553B

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