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Issue 29, 2013
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Immuno-CoPS (conducting paper strips) for futuristic cost-effective cancer diagnostics

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Abstract

The fabrication of cost-effective, rapid and specific paper based point-of-care (POC) diagnostics based on the principles of bio-recognition is currently at the vanguard of biomedical research, as it is playing a key role in early diagnosis and treatment, resulting in the inhibition of infection and reducing the mortality rate. In the present report, we demonstrate that biomolecules can be directly attached to a paper matrix covalently, by suitable modification of the paper matrices. A high conductivity is achieved and the porosity can be tailored and has been utilized for the quantitative estimation of bio-analytes. We prove the feasibility of our approach for the detection of cancer biomarkers in a wide detection range.

Graphical abstract: Immuno-CoPS (conducting paper strips) for futuristic cost-effective cancer diagnostics

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Article information


Submitted
29 Jan 2013
Accepted
06 May 2013
First published
07 May 2013

RSC Adv., 2013,3, 11846-11853
Article type
Paper

Immuno-CoPS (conducting paper strips) for futuristic cost-effective cancer diagnostics

S. Kumar, K. K. Jagadeesan, A. G. Joshi and G. Sumana, RSC Adv., 2013, 3, 11846
DOI: 10.1039/C3RA40491A

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