Chrysanolide A, an unprecedented sesquiterpenoid trimer from the flowers of Chrysanthemum indicum L

Qiong Gu; Yaoyao Chen; Hui Cui; Dane Huang; Jingwei Zhou; Taizong Wu; Yiping Chen; Lina Shi; Jun Xu

doi:10.1039/C3RA23172K

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Chrysanolide A, an unprecedented sesquiterpenoid trimer from the flowers of Chrysanthemum indicum L†

Qiong Gu,*^a Yaoyao Chen,^b Hui Cui,^a Dane Huang,^a Jingwei Zhou,^a Taizong Wu,^a Yiping Chen,^b Lina Shi^a and Jun Xu^a

Author affiliations

* Corresponding authors

^a Research Center for Drug Discovery & Institute of Human Virology, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P.R. China
E-mail: guqiong@mail.sysu.edu.cn
Fax: +86-20-39943077
Tel: +86-20-39943077

^b Guangxi University of Chinese Medicine, Guangxi 530001, P.R. China

Abstract

Chrysanolide A, a novel guaianolide-type sesquiterpenoid trimer (3), along with its biogenetically related monomer (Chrysanolide B, 1) and dimer (Chrysanolide C, 2), were simultaneously isolated from Chrysanthemum indicum L flowers. Their structures and absolute configurations were elucidated via spectroscopic and computational methods. All isolated compounds were evaluated for their anti-HBV activities.

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Article information

DOI: https://doi.org/10.1039/C3RA23172K
Article type: Communication
Submitted: 05 Dec 2012
Accepted: 03 Apr 2013
First published: 13 May 2013

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RSC Adv., 2013,3, 10168-10172

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Chrysanolide A, an unprecedented sesquiterpenoid trimer from the flowers of Chrysanthemum indicum L

Q. Gu, Y. Chen, H. Cui, D. Huang, J. Zhou, T. Wu, Y. Chen, L. Shi and J. Xu, RSC Adv., 2013, 3, 10168 DOI: 10.1039/C3RA23172K

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Chrysanolide A, an unprecedented sesquiterpenoid trimer from the flowers of Chrysanthemum indicum L†

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Chrysanolide A, an unprecedented sesquiterpenoid trimer from the flowers of Chrysanthemum indicum L

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