Issue 8, 2013
From the journal:

RSC Advances

Exploring the fluorescence switching phenomenon of curcumin encapsulated niosomes: in vitro real time monitoring of curcumin release to cancer cells†

Nagaprasad Puvvada,a   Shashi Rajput,b   B. N. Prashanth Kumar,b   Mahitosh Mandalb  and  Amita Pathak*a  

* Corresponding authors

a Department of Chemistry, Kharagpur-721302, West Bengal, India
E-mail: ami@chem.iitkgp.ernet.in

b School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur-721302, West Bengal, India

Abstract

This is the first report on the reversible fluorescence switching of curcumin encapsulated niosomes exhibiting a strong blue color excimer emission in the UV region and a green color luminescence of the excited state monomer form of curcumin that undergoes ESIPT in the visible region. The real time monitoring of the release of curcumin from niosomes is feasible through the change of fluorescence color from blue to green.

Graphical abstract: Exploring the fluorescence switching phenomenon of curcumin encapsulated niosomes: in vitro real time monitoring of curcumin release to cancer cells

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Article information

DOI
https://doi.org/10.1039/C2RA23382G
Article type
Communication
Submitted
07 Nov 2012
Accepted
07 Jan 2013
First published
08 Jan 2013

RSC Adv., 2013,3, 2553-2557

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Exploring the fluorescence switching phenomenon of curcumin encapsulated niosomes: in vitro real time monitoring of curcumin release to cancer cells

N. Puvvada, S. Rajput, B. N. P. Kumar, M. Mandal and A. Pathak, RSC Adv., 2013, 3, 2553 DOI: 10.1039/C2RA23382G

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