Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 39, 2013
Previous Article Next Article

Diastereoselective synthesis of the C14–C29 fragment of amphidinol 3

Author affiliations

Abstract

An efficient stereoselective synthesis of the C14–C29 fragment highlighting a coupling reaction between a 1,3-dithiane derivative and an α-branched aldehyde was realized. This highly convergent synthesis involved two chiral pools, L-malic acid and (+)-camphorsulfonic acid, which are the starting compounds to control the six stereogenic centers present in the C14–C29 fragment of amphidinol 3.

Graphical abstract: Diastereoselective synthesis of the C14–C29 fragment of amphidinol 3

Back to tab navigation

Supplementary files

Article information


Submitted
31 Jul 2013
Accepted
15 Aug 2013
First published
15 Aug 2013

Org. Biomol. Chem., 2013,11, 6829-6840
Article type
Paper

Diastereoselective synthesis of the C14–C29 fragment of amphidinol 3

N. Rival, G. Hanquet, C. Bensoussan, S. Reymond, J. Cossy and F. Colobert, Org. Biomol. Chem., 2013, 11, 6829
DOI: 10.1039/C3OB41569D

Social activity

Search articles by author

Spotlight

Advertisements