Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 24, 2013
Previous Article Next Article

Chemical approaches for detection and destruction of nerve agents

Author affiliations

Abstract

Since the introduction of organophosphorus (OP) compounds as nerve agents and pesticides, methods of dealing with their toxicity to humans have been intensely researched. There are studies on sensing, pretreatments, prophylactics, antidotes and therapies. There is some overlap in all of these endeavors because they have to deal with the reactivity of the phosphorus atom in various contexts. The contexts range from large spaces, the thinly spread vapors in the air, to very small spaces in the active sites of enzymes – acetylcholinesterase (AChE) or butyrylcholinesterase (BuChE) – that have reacted with the OP agent.

Graphical abstract: Chemical approaches for detection and destruction of nerve agents

Back to tab navigation

Publication details

The article was received on 14 Feb 2013, accepted on 19 Mar 2013 and first published on 20 Mar 2013


Article type: Perspective
DOI: 10.1039/C3OB40324F
Citation: Org. Biomol. Chem., 2013,11, 3936-3942

  •   Request permissions

    Chemical approaches for detection and destruction of nerve agents

    D. Ajami and J. Rebek, Org. Biomol. Chem., 2013, 11, 3936
    DOI: 10.1039/C3OB40324F

Search articles by author

Spotlight

Advertisements