Issue 17, 2013
From the journal:

Organic & Biomolecular Chemistry

Concise total syntheses of (±)-noruleine and (±)-uleine†

Süleyman Patir*a  and  Erkan Ertürk*b  

* Corresponding authors

a Department of Chemistry Education, Faculty of Education, Hacettepe University, 06800 Beytepe, Ankara, Turkey
E-mail: patir@hacettepe.edu.tr

b Chemistry Institute, TUBITAK Marmara Research Center, 41470 Gebze, Kocaeli, Turkey
E-mail: erkan.erturk@tubitak.gov.tr
Fax: +90-262-641 2309
Tel: +90-262-677 2993

Abstract

The first total synthesis of (±)-noruleine and a concise synthesis of (±)-uleine have been accomplished via the DDQ mediated dehydrogenative cyclization of a tetrahydrocarbazole derivative bearing a non-substituted amide functionality to prepare the key azocino[4,3-b]indole precursor.

Graphical abstract: Concise total syntheses of (±)-noruleine and (±)-uleine

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Article information

DOI
https://doi.org/10.1039/C3OB40180D
Article type
Paper
Submitted
26 Jan 2013
Accepted
26 Feb 2013
First published
27 Feb 2013

Org. Biomol. Chem., 2013,11, 2804-2810

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Concise total syntheses of (±)-noruleine and (±)-uleine

S. Patir and E. Ertürk, Org. Biomol. Chem., 2013, 11, 2804 DOI: 10.1039/C3OB40180D

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