Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing†
Abstract
We recently reported the use of PSCl3 for the thiophosphorylation of
* Corresponding authors
a
Department of Chemistry, Science Laboratories, Durham University, South Road, Durham, United Kingdom
E-mail:
d.r.w.hodgson@durham.ac.uk
b School of Medicine and Health, Queen's Campus, Stockton-on-Tees, United Kingdom
c School of Biological and Biomedical Sciences, Science Laboratories, Durham University, South Road, Durham, United Kingdom
We recently reported the use of PSCl3 for the thiophosphorylation of
M. Trmčić, F. L. Chadbourne, P. M. Brear, P. W. Denny, S. L. Cobb and D. R. W. Hodgson, Org. Biomol. Chem., 2013, 11, 2660 DOI: 10.1039/C3OB27448A
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