α-Hydroxy-β-keto acid rearrangement–decarboxylation: impact on thiamine diphosphate-dependent enzymatic transformations†
Abstract
The thiamine diphosphate (
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* Corresponding authors
a
Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstraße 25, 79104 Freiburg, Germany
E-mail:
michael.mueller@pharmazie.uni-freiburg.de
Tel: +49-761-2036335
b Institute of Organic Chemistry and Biochemistry and BIOSS Center for Biological Signaling Studies, Albert-Ludwigs-Universität Freiburg, Albertstraße 21, 79104 Freiburg, Germany
c Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
d Institute of Molecular Enzyme Technology at the Heinrich-Heine-University of Düsseldorf, Research Centre, 52426 Jülich, Germany
The thiamine diphosphate (
M. Beigi, S. Loschonsky, P. Lehwald, V. Brecht, S. L. A. Andrade, F. J. Leeper, W. Hummel and M. Müller, Org. Biomol. Chem., 2013, 11, 252 DOI: 10.1039/C2OB26981C
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