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Issue 1, 2013
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Structural stabilization of DNA-templated nanostructures: crosslinking with 2,5-bis(2-thienyl)pyrrole monomers

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Abstract

Ordered 2,5-bis(2-thienyl)pyrrole (SNS) zipper arrays are formed by hybridization of complementary DNA oligomers each containing covalently bound SNS monomers. Upon oxidation with HRP/H2O2, these SNS arrays are converted to oligomers having specific lengths and conformation. As a consequence of this reaction the two SNS-containing strands are permanently crosslinked.

Graphical abstract: Structural stabilization of DNA-templated nanostructures: crosslinking with 2,5-bis(2-thienyl)pyrrole monomers

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Publication details

The article was received on 30 Aug 2012, accepted on 09 Oct 2012 and first published on 12 Oct 2012


Article type: Communication
DOI: 10.1039/C2OB26716K
Org. Biomol. Chem., 2013,11, 35-40

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    Structural stabilization of DNA-templated nanostructures: crosslinking with 2,5-bis(2-thienyl)pyrrole monomers

    W. Chen and G. B. Schuster, Org. Biomol. Chem., 2013, 11, 35
    DOI: 10.1039/C2OB26716K

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