Jump to main content
Jump to site search

Issue 48, 2013
Previous Article Next Article

An organocatalytic highly efficient approach to the direct synthesis of substituted carbazoles in water

Author affiliations

Abstract

A simple, mild, green, catalytic and general procedure for the direct synthesis of highly functionalized 1-methoxycarbonyl-2-aryl/alkyl-3-nitro-9H-carbazoles has been achieved in water medium via a one-pot domino Michael–Henry/aromatization reaction of methyl 2-(3-formyl-1H-indol-2-yl)acetates with aryl/alky-substituted β-nitroolefins under air using DABCO (30 mol%) as an organocatalyst. In addition, the bench scale synthesis can be performed without using toxic organic solvents and a biologically important new fused carbazole has been prepared.

Graphical abstract: An organocatalytic highly efficient approach to the direct synthesis of substituted carbazoles in water

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Oct 2013, accepted on 17 Oct 2013 and first published on 17 Oct 2013


Article type: Paper
DOI: 10.1039/C3OB42034E
Org. Biomol. Chem., 2013,11, 8410-8418

  •   Request permissions

    An organocatalytic highly efficient approach to the direct synthesis of substituted carbazoles in water

    P. K. Jaiswal, S. Biswas, S. Singh and S. Samanta, Org. Biomol. Chem., 2013, 11, 8410
    DOI: 10.1039/C3OB42034E

Search articles by author

Spotlight

Advertisements