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Issue 24, 2013
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Quantum dot approaches for target-based drug screening and multiplexed active biosensing

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Abstract

Biomolecule detection using quantum dots (Qdots), nanometer-sized semiconductor crystals, effectively addresses the limitations associated with conventional optical and biochemical techniques, as Qdots offer several key advantages over traditional fluorophores. In this minireview, we discuss the role of Qdots as a central nanoscaffold for the polyvalent assembly of multifunctional biomolecular probes and describe recent advances in Qdot-based biorecognition. Specifically, we focus on Qdot applications in target-based, drug screening assays and real-time active biosensing of cellular processes.

Graphical abstract: Quantum dot approaches for target-based drug screening and multiplexed active biosensing

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Article information


Submitted
23 Apr 2013
Accepted
27 Jul 2013
First published
14 Aug 2013

Nanoscale, 2013,5, 12072-12081
Article type
Minireview

Quantum dot approaches for target-based drug screening and multiplexed active biosensing

O. Kovtun, X. Arzeta-Ferrer and S. J. Rosenthal, Nanoscale, 2013, 5, 12072
DOI: 10.1039/C3NR02019C

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