Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 7, 2013
Previous Article Next Article

Three-dimensional quantitative force maps in liquid with 10 piconewton, angstrom and sub-minute resolutions

Author affiliations

Abstract

We develop a bimodal force microscopy method to map the three-dimensional force fields and their time-evolution on a variety of solid–water interfaces. The force maps show an oscillatory decaying force perpendicular to the solid surface with a 0.3 nm periodicity. The technique enables the three-dimensional imaging and mapping of the hydration layers and forces on mica and protein GroEL surfaces with 10 piconewton, 2 angstrom and 40 second (whole volume) resolutions. We record the existence and evolution of nanoscale perturbations involving thousands of water molecules of the protein–liquid interface. Those instabilities are not found in stiff and atomically flat interfaces.

Graphical abstract: Three-dimensional quantitative force maps in liquid with 10 piconewton, angstrom and sub-minute resolutions

Back to tab navigation

Supplementary files

Article information


Submitted
05 Oct 2012
Accepted
18 Nov 2012
First published
12 Dec 2012

Nanoscale, 2013,5, 2678-2685
Article type
Paper

Three-dimensional quantitative force maps in liquid with 10 piconewton, angstrom and sub-minute resolutions

E. T. Herruzo, H. Asakawa, T. Fukuma and R. Garcia, Nanoscale, 2013, 5, 2678
DOI: 10.1039/C2NR33051B

Social activity

Search articles by author

Spotlight

Advertisements