Issue 2, 2013
From the journal:

New Journal of Chemistry

Fully supramolecular vesicles as anticancer drug delivery systems†

Ali Pourjavadi,*a   Mohsen Adeli*ab  and  Mojtaba Yazdia  

* Corresponding authors

a Department of Chemistry, Sharif University of Technology, Tehran, Iran

b Department of Chemistry, Faculty of Science, Lorestan University, Khoramabad, Iran
E-mail: mohadeli@yahoo.com
Fax: +98 661-2202782
Tel: +98 916-3603772

Abstract

A supramolecular linear-dendritic copolymer consisting of a polystyrene backbone and hanging hyperbranched polyglycerols was prepared and characterized. Host–guest interactions between β-cyclodextrin incorporated in the core of polyglycerol as a host and aromatic rings of polystyrene as guests lead to the formation of a supramolecular linear-dendritic copolymer. Supramolecules formed micelles in aqueous solutions which were able to encapsulate and transfer paclitaxel with a high loading capacity.

Graphical abstract: Fully supramolecular vesicles as anticancer drug delivery systems

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Article information

DOI
https://doi.org/10.1039/C2NJ40851A
Article type
Letter
Submitted
19 Sep 2012
Accepted
24 Nov 2012
First published
28 Nov 2012

New J. Chem., 2013,37, 295-298

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Fully supramolecular vesicles as anticancer drug delivery systems

A. Pourjavadi, M. Adeli and M. Yazdi, New J. Chem., 2013, 37, 295 DOI: 10.1039/C2NJ40851A

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