Synthesis, cytotoxicity and hDHFR inhibition studies of 2H-pyrido[1,2-a]pyrimidin-2-ones†
Abstract
Synthesis of the titled scaffolds was achieved by the condensation of Baylis–Hillman acetates with 2-aminopyridines under
* Corresponding authors
a
Crop Protection Chemicals Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India
E-mail:
manjula@iict.res.in
Fax: +91 040 27193382
Tel: +91 040 27191441
b
Centre for Chemical Biology, Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India
E-mail:
anthony@iict.res.in
Synthesis of the titled scaffolds was achieved by the condensation of Baylis–Hillman acetates with 2-aminopyridines under
S. Rapolu, M. Alla, R. J. Ganji, V. Saddanapu, C. Kishor, V. R. Bommena and A. Addlagatta, Med. Chem. Commun., 2013, 4, 817 DOI: 10.1039/C3MD00013C
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