Issue 13, 2013

On-chip nanohole array based sensing: a review


The integration of nanohole array based plasmonic sensors into microfluidic systems has enabled the emergence of platforms with unique capabilities and a diversified palette of applications. Recent advances in fabrication techniques together with novel implementation schemes have influenced the progress of these optofluidic platforms. Here, we review the advances that nanohole array based sensors have experienced since they were first merged with microfluidics. We examine established and new fabrication methodologies that have enabled both the fabrication of nanohole arrays with improved optical attributes and a reduction in manufacturing costs. The achievements of several platforms developed to date and the significant benefits obtained from operating the nanoholes as nanochannels are also reviewed herein. Finally, we discuss future opportunities for on-chip nanohole array sensors by outlining potential applications and the use of the abilities of the nanostructures beyond the optical context.

Graphical abstract: On-chip nanohole array based sensing: a review

Article information

Article type
Critical Review
23 Jan 2013
06 Mar 2013
First published
06 Mar 2013
This article is Open Access
Creative Commons BY license

Lab Chip, 2013,13, 2445-2463

On-chip nanohole array based sensing: a review

C. Escobedo, Lab Chip, 2013, 13, 2445 DOI: 10.1039/C3LC50107H

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