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Issue 8, 2013
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Micro-optical lens array for fluorescence detection in droplet-based microfluidics

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Abstract

We demonstrate the design and integration of droplet-based microfluidic devices with microoptical element arrays for enhanced detection of fluorescent signals. We show that the integration of microlenses and mirror surfaces in these devices results in an 8-fold increase in the fluorescence signal and in improved spatial resolution. Using an array of microlenses, massively parallel detection of droplets containing fluorescent dyes was achieved, leading to detection throughputs of about 2000 droplets per second and per lens, parallelized over 625 measurement points.

Graphical abstract: Micro-optical lens array for fluorescence detection in droplet-based microfluidics

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Supplementary files

Article information


Submitted
04 Dec 2012
Accepted
29 Jan 2013
First published
30 Jan 2013

This article is Open Access

Lab Chip, 2013,13, 1472-1475
Article type
Technical Innovation

Micro-optical lens array for fluorescence detection in droplet-based microfluidics

J. Lim, P. Gruner, M. Konrad and J. Baret, Lab Chip, 2013, 13, 1472
DOI: 10.1039/C3LC41329B

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