Jump to main content
Jump to site search

Issue 11, 2013

A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin

Author affiliations

Abstract

Cylindrospermopsin is an important cyanobacterial toxin found in water bodies worldwide. The ever-increasing and global occurrence of massive and prolonged blooms of cylindrospermopsin-producing cyanobacteria poses a potential threat to both human and ecosystem health. Its toxicity is associated with metabolic activation and may involve mechanisms that adversely affect a wide variety of targets in an organism. Cylindrospermopsin has been shown to be cytotoxic, dermatotoxic, genotoxic, hepatotoxic in vivo, developmentally toxic, and may be carcinogenic. Human exposure may occur through drinking water, during recreational activities and by consuming foods in which the toxin may have bioaccumulated. Drinking water shortages of sufficient quality coupled with growing human pressures and climate variability and change necessitate an integrated and sustainable water management program. This review presents an overview of the importance of cylindrospermopsin, its detection, toxicity, worldwide distribution, and lastly, its chemical and biological degradation and removal by natural processes and drinking water treatment processes.

Graphical abstract: A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin

Article information


Submitted
05 Jul 2013
Accepted
28 Aug 2013
First published
29 Aug 2013

Environ. Sci.: Processes Impacts, 2013,15, 1979-2003
Article type
Critical Review

A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin

A. A. de la Cruz, A. Hiskia, T. Kaloudis, N. Chernoff, D. Hill, M. G. Antoniou, X. He, K. Loftin, K. O'Shea, C. Zhao, M. Pelaez, C. Han, T. J. Lynch and D. D. Dionysiou, Environ. Sci.: Processes Impacts, 2013, 15, 1979 DOI: 10.1039/C3EM00353A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements