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Issue 22, 2013
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Waveguide-enhanced mid-infrared chem/bio sensors

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Despite providing the opportunity for directly sensing molecular constituents with inherent fingerprint specificity in the 2.5–20 μm spectral regime, mid-infrared optical sensing technologies have not yet achieved the same penetration in waveguide-based chem/bio sensing compared to related sensing schemes operating at visible and near-infrared frequencies. In this review, current advances in mid-infrared chem/bio sensor technology will be highlighted and contrasted with the prevalent bottlenecks that have to date limited a more widespread adoption of mid-infrared sensing devices. However, with the increasing availability of advanced light sources such as quantum cascade lasers and the advent of on-chip semiconductor waveguide technologies, a prosperous future of this sensing concept for label-free detection in environmental analysis, process monitoring, and bioanalytics is perceived.

Graphical abstract: Waveguide-enhanced mid-infrared chem/bio sensors

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Article information

29 May 2013
First published
30 Aug 2013

Chem. Soc. Rev., 2013,42, 8683-8699
Article type
Review Article

Waveguide-enhanced mid-infrared chem/bio sensors

B. Mizaikoff, Chem. Soc. Rev., 2013, 42, 8683
DOI: 10.1039/C3CS60173K

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