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Issue 10, 2013
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Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics

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Abstract

Fluoro-C-glycosides and fluoro-carbasugars are a particular subclass of hydrolytically stable glycomimetics that are expected to have different, hopefully improved properties thanks to the stereoelectronic features of the fluoroalkyl moiety. This review summarizes the studies devoted to the synthesis of such structures as well as the studies regarding their conformational behaviour and their potential as carbohydrate analogues.

Graphical abstract: Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics

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Article information


Submitted
01 Oct 2012
First published
04 Dec 2012

Chem. Soc. Rev., 2013,42, 4270-4283
Article type
Tutorial Review

Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics

E. Leclerc, X. Pannecoucke, M. Ethève-Quelquejeu and M. Sollogoub, Chem. Soc. Rev., 2013, 42, 4270
DOI: 10.1039/C2CS35403A

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