Issue 85, 2013
From the journal:

Chemical Communications

Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells†

Peng An,a   Zhipeng Yua  and  Qing Lin*a  

* Corresponding authors

a Department of Chemistry, State University of New York at Buffalo, Buffalo, NY 14260, USA
E-mail: qinglin@buffalo.edu

Abstract

A 405 nm light-activatable terthiophene-based tetrazole was designed that reacts with a fumarate dipolarophile with the second-order rate constant k2 exceeding 103 M−1 s−1. The utility of this laser-activatable tetrazole in imaging microtubules in a spatiotemporally controlled manner in live cells was demonstrated.

Graphical abstract: Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells

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Article information

DOI
https://doi.org/10.1039/C3CC45752D
Article type
Communication
Submitted
27 Jul 2013
Accepted
03 Sep 2013
First published
03 Sep 2013

Chem. Commun., 2013,49, 9920-9922

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Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells

P. An, Z. Yu and Q. Lin, Chem. Commun., 2013, 49, 9920 DOI: 10.1039/C3CC45752D

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