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Issue 93, 2013
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Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery

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Abstract

Enhanced selectivity and efficacy is important for advanced drug delivery. Herein, a novel type of folic acid conjugated self-assembled layered double hydroxide nanoparticles is reported. These nanoparticles have a drug loading capacity of 27 wt% and are able to enter cell nuclei and dramatically improve the efficacy of MTX.

Graphical abstract: Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery

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Supplementary files

Article information


Submitted
26 Jul 2013
Accepted
02 Oct 2013
First published
02 Oct 2013

Chem. Commun., 2013,49, 10938-10940
Article type
Communication

Folic acid conjugated self-assembled layered double hydroxide nanoparticles for high-efficacy-targeted drug delivery

L. Yan, W. Chen, X. Zhu, L. Huang, Z. Wang, G. Zhu, V. A. L. Roy, K. N. Yu and X. Chen, Chem. Commun., 2013, 49, 10938 DOI: 10.1039/C3CC45714A

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