Issue 74, 2013
From the journal:

Chemical Communications

Oxidation of 2-arylindoles for synthesis of 2-arylbenzoxazinones with oxone as the sole oxidant†

Xiao-Li Lian,a   Hao Lei,a   Xue-Jing Quan,a   Zhi-Hui Ren,a   Yao-Yu Wanga  and  Zheng-Hui Guan*a  

* Corresponding authors

a Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710069, P. R. China
E-mail: guanzhh@nwu.edu.cn

Abstract

A novel and efficient method for the oxidation of 2-arylindoles to synthesize 2-arylbenzoxazinones utilizing oxone as the sole oxidant has been developed. The reaction tolerates a wide range of functional groups and allows quick and atom-economical assembly of a variety of valuable 2-arylbenzoxazinones in high yields.

Graphical abstract: Oxidation of 2-arylindoles for synthesis of 2-arylbenzoxazinones with oxone as the sole oxidant

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Article information

DOI
https://doi.org/10.1039/C3CC44215B
Article type
Communication
Submitted
05 Jun 2013
Accepted
17 Jul 2013
First published
17 Jul 2013

Chem. Commun., 2013,49, 8196-8198

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Oxidation of 2-arylindoles for synthesis of 2-arylbenzoxazinones with oxone as the sole oxidant

X. Lian, H. Lei, X. Quan, Z. Ren, Y. Wang and Z. Guan, Chem. Commun., 2013, 49, 8196 DOI: 10.1039/C3CC44215B

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