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Issue 61, 2013
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Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

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Abstract

A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.

Graphical abstract: Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

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Article information


Submitted
28 May 2013
Accepted
10 Jun 2013
First published
11 Jun 2013

Chem. Commun., 2013,49, 6858-6860
Article type
Communication

Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

N. K. Mani, S. Rudiuk and D. Baigl, Chem. Commun., 2013, 49, 6858
DOI: 10.1039/C3CC44016H

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