Issue 59, 2013
From the journal:

Chemical Communications

A dual-functional electrochemical biosensor for the detection of prostate specific antigen and telomerase activity†

Jing Liu,a   Cai-Yu Lu,b   Hong Zhou,a   Jing-Juan Xu,*a   Zong-Hua Wangb  and  Hong-Yuan Chen*a  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
E-mail: xujj@nju.edu.cn, hychen@nju.edu.cn
Fax: +86-25-83594862
Tel: +86-25-83597924

b Department of Chemistry, Qingdao University, Qingdao 266071, China

Abstract

A new dual-functional electrochemical biosensor for the detection of prostate specific antigen (PSA) and telomerase activity was successfully developed based on a sandwich immunobinding format and telomerization assisted hemin–G-quadruplex-based DNAzyme as a biolabel.

Graphical abstract: A dual-functional electrochemical biosensor for the detection of prostate specific antigen and telomerase activity

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Article information

DOI
https://doi.org/10.1039/C3CC43532F
Article type
Communication
Submitted
11 May 2013
Accepted
31 May 2013
First published
03 Jun 2013

Chem. Commun., 2013,49, 6602-6604

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A dual-functional electrochemical biosensor for the detection of prostate specific antigen and telomerase activity

J. Liu, C. Lu, H. Zhou, J. Xu, Z. Wang and H. Chen, Chem. Commun., 2013, 49, 6602 DOI: 10.1039/C3CC43532F

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