Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 61, 2013
Previous Article Next Article

N-terminal α-amino group modification of peptides by an oxime formation–exchange reaction sequence

Author affiliations

Abstract

A site-specific and efficient method for N-terminal modification of peptides using oxone for selective oxidation of N-terminal α-amino groups of peptides to oximes followed by transoximation with O-substituted hydroxylamines has been developed.

Graphical abstract: N-terminal α-amino group modification of peptides by an oxime formation–exchange reaction sequence

Back to tab navigation

Supplementary files

Article information


Submitted
28 Mar 2013
Accepted
11 Jun 2013
First published
11 Jun 2013

Chem. Commun., 2013,49, 6888-6890
Article type
Communication

N-terminal α-amino group modification of peptides by an oxime formation–exchange reaction sequence

K. K. Kung, K. Wong, K. Leung and M. Wong, Chem. Commun., 2013, 49, 6888
DOI: 10.1039/C3CC42261E

Social activity

Search articles by author

Spotlight

Advertisements