Issue 48, 2013
From the journal:

Chemical Communications

An aptamer-gated silica mesoporous material for thrombin detection†

Mar Oroval,abc   Estela Climent,abc   Carmen Coll,abc   Ramón Eritja,*cd   Anna Aviñó,cd   Maria Dolores Marcos,abc   Félix Sancenón,abc   Ramón Martínez-Máñez*abc  and  Pedro Amoróse  

* Corresponding authors

a Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universidad Politécnica de Valencia - Universidad de Valencia, Spain

b Departamento de Química, Universidad Politécnica de Valencia, Camino de Vera s/n, Valencia, Spain
E-mail: rmaez@qim.upv.es

c CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain

d Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, Jordi Girona 18-26, E-08034 Barcelona, Spain

e Institut de Ciència dels Materials (ICMUV), Universitat de Valencia, P.O. Box 2085, E-46071 Valencia, Spain

Abstract

An aptamer-capped mesoporous material for the selective and sensitive detection of α-thrombin in human plasma and serum has been prepared and characterised.

Graphical abstract: An aptamer-gated silica mesoporous material for thrombin detection

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Article information

DOI
https://doi.org/10.1039/C3CC42157K
Article type
Communication
Submitted
25 Mar 2013
Accepted
25 Apr 2013
First published
25 Apr 2013

Chem. Commun., 2013,49, 5480-5482

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An aptamer-gated silica mesoporous material for thrombin detection

M. Oroval, E. Climent, C. Coll, R. Eritja, A. Aviñó, M. D. Marcos, F. Sancenón, R. Martínez-Máñez and P. Amorós, Chem. Commun., 2013, 49, 5480 DOI: 10.1039/C3CC42157K

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