Issue 46, 2013
From the journal:

Chemical Communications

Palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines†

Jin-Biao Liu,a   Hui Yan,a   Hui-Xuan Chen,a   Yu Luo,a   Jiang Wenga  and  Gui Lu*ab  

* Corresponding authors

a Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, P. R. China
E-mail: lugui@mail.sysu.edu.cn
Fax: +86-20-39943048

b Institute of Human Virology, Sun Yat-sen University, Guangzhou, P. R. China

Abstract

The first palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines with various organoboron reagents has been developed for the preparation of biaryl compounds in high yields. N′-Tosyl arylhydrazine as a readily available and stable electrophile also demonstrated its generality in a number of coupling reactions.

Graphical abstract: Palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines

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Article information

DOI
https://doi.org/10.1039/C3CC41421C
Article type
Communication
Submitted
24 Feb 2013
Accepted
15 Apr 2013
First published
19 Apr 2013

Chem. Commun., 2013,49, 5268-5270

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Palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines

J. Liu, H. Yan, H. Chen, Y. Luo, J. Weng and G. Lu, Chem. Commun., 2013, 49, 5268 DOI: 10.1039/C3CC41421C

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