Rongshun Chen, Silong Xu, Liyi Wang, Yuhai Tang and Zhengjie He
Chem. Commun., 2013,49, 3543-3545
DOI:
10.1039/C3CC41419A,
Communication
Amine-catalyzed [2 + 2 + 2] and [2 + 4] annulations of Morita–Baylis–Hillman (MBH) acetates with cyano activated alkenes and 1,3-azadienes have been developed to provide cyclohexanes and tetrahydropyridines. In the annulations, MBH acetates serve as a novel C2 component with an inactive homoallylic methyl involved in the bond formation.
![Graphical abstract: Distinct reactivity of Morita–Baylis–Hillman acetates as a novel C2 component in amine-catalyzed [2 + 2 + 2] and [2 + 4] annulations](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C3CC41419A "Graphical abstract")
