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A photo-, acid- and thermo-responsive nitrobenzene-based amphiphilic copolymer was synthesized and the corresponding multi-responsive behavior of the copolymer assemblies was revealed by TEM, DLS and AFM. The morphological changes of the assemblies under multi-stimuli endowed them with a controlled release of encapsulated molecules.

Graphical abstract: Multi-responsive nitrobenzene-based amphiphilic random copolymer assemblies

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