Issue 19, 2013
From the journal:

Chemical Communications

Simultaneous profiling of multiple gene-methylation loci by electrochemical methylation-specific ligase detection reaction†

Zong Dai,*a   Ting Cai,a   Wenyuan Zhu,a   Xiaoyu Gaoa  and  Xiaoyong Zoua  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, P. R. China
E-mail: daizong@mail.sysu.edu.cn
Fax: +86 20 84112245
Tel: +86 20 84114919

Abstract

A novel method of electrochemical methylation-specific ligation detection reaction is first presented for simultaneous evaluation of multiple gene-methylation loci in a single-tube experiment without PCR amplification or restriction enzyme reaction.

Graphical abstract: Simultaneous profiling of multiple gene-methylation loci by electrochemical methylation-specific ligase detection reaction

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Article information

DOI
https://doi.org/10.1039/C3CC38942A
Article type
Communication
Submitted
14 Dec 2012
Accepted
18 Jan 2013
First published
21 Jan 2013

Chem. Commun., 2013,49, 1939-1941

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Simultaneous profiling of multiple gene-methylation loci by electrochemical methylation-specific ligase detection reaction

Z. Dai, T. Cai, W. Zhu, X. Gao and X. Zou, Chem. Commun., 2013, 49, 1939 DOI: 10.1039/C3CC38942A

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