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Issue 16, 2013
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A mild method for generation of o-quinone methides under basic conditions. The facile synthesis of trans-2,3-dihydrobenzofurans

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Abstract

A novel and efficient method for the generation of o-quinone methide intermediates was developed from the readily available 2-tosylalkylphenols under the mild basic conditions, and their reactions with sulfur ylides were investigated for the stereoselective synthesis of trans-2,3-dihydrobenzofurans.

Graphical abstract: A mild method for generation of o-quinone methides under basic conditions. The facile synthesis of trans-2,3-dihydrobenzofurans

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Article information


Submitted
27 Oct 2012
Accepted
07 Jan 2013
First published
08 Jan 2013

Chem. Commun., 2013,49, 1660-1662
Article type
Communication

A mild method for generation of o-quinone methides under basic conditions. The facile synthesis of trans-2,3-dihydrobenzofurans

M. Chen, L. Cao, Z. Ye, G. Jiang and Y. Zhou, Chem. Commun., 2013, 49, 1660
DOI: 10.1039/C3CC37800D

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