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Issue 19, 2013

Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

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Abstract

Simple and general cancer cell detection methods are required in point-of-care diagnostics. Herein, the interaction between an anticancer drug, daunomycin, and cancer cell membrane components has been studied using an aptamer probe immobilized on a conducting polymergold nanoparticle composite film through electrochemical and fluorescence methods and applied to the quantitative detection of cancer cells. The developed method differentiates between cancerous and noncancerous cells effectively.

Graphical abstract: Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

Supplementary files

Article information


Submitted
15 Nov 2012
Accepted
20 Dec 2012
First published
21 Dec 2012

Chem. Commun., 2013,49, 1900-1902
Article type
Communication

Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

P. Chandra, H. Noh and Y. Shim, Chem. Commun., 2013, 49, 1900 DOI: 10.1039/C2CC38235K

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