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Issue 39, 2013
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N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

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Abstract

Metabolic chemical reporters of glycosylation allow for the visualization and identification of a variety of glycoconjugates by taking advantage of the promiscuity of carbohydrate metabolism. Here we describe the synthesis and characterization of metabolic chemical reporters bearing an N-propargyloxycarbamate (Poc) group that creates discrimination between glycosylation pathways.

Graphical abstract: N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

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Article information


Submitted
02 Nov 2012
Accepted
03 Dec 2012
First published
03 Dec 2012

Chem. Commun., 2013,49, 4328-4330
Article type
Communication

N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

L. A. Bateman, B. W. Zaro, K. N. Chuh and M. R. Pratt, Chem. Commun., 2013, 49, 4328
DOI: 10.1039/C2CC37963E

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