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Issue 39, 2013
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N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

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Abstract

Metabolic chemical reporters of glycosylation allow for the visualization and identification of a variety of glycoconjugates by taking advantage of the promiscuity of carbohydrate metabolism. Here we describe the synthesis and characterization of metabolic chemical reporters bearing an N-propargyloxycarbamate (Poc) group that creates discrimination between glycosylation pathways.

Graphical abstract: N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

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Publication details

The article was received on 02 Nov 2012, accepted on 03 Dec 2012 and first published on 03 Dec 2012


Article type: Communication
DOI: 10.1039/C2CC37963E
Chem. Commun., 2013,49, 4328-4330

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    N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

    L. A. Bateman, B. W. Zaro, K. N. Chuh and M. R. Pratt, Chem. Commun., 2013, 49, 4328
    DOI: 10.1039/C2CC37963E

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