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Issue 6, 2013
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Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68

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Abstract

Pre-organised tricarboxylate ligands based on 6-amino-perhydro-1,4-diazepine bind 68Ga rapidly and selectively in acetate buffer at pH 4 to 7, forming kinetically stable complexes suitable for use in PET imaging.

Graphical abstract: Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68

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Publication details

The article was received on 16 Oct 2012, accepted on 13 Nov 2012 and first published on 14 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC37544C
Citation: Chem. Commun., 2013,49, 579-581

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    Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68

    B. P. Waldron, D. Parker, C. Burchardt, D. S. Yufit, M. Zimny and F. Roesch, Chem. Commun., 2013, 49, 579
    DOI: 10.1039/C2CC37544C

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